Clem Jones Centre for Regenerative Medicine (CJCRM)
Bond University
Formerly known as Clem Jones Research Centre for Regenerative Medicine
The Centre investigates the therapeutic use of stem cells in tissue repair. Stem cells hold immense promise in regenerative medicine with the ability to differentiate into any cell type. The Centre goal is halting and reversing vision loss in retinal disease conditions, such as age-related macular degeneration (AMD). Research is cross-disciplinary and focuses on using targeted and precisely defined conditions to produce stem cell derived retinal cells for tissue repair and utilising neuroprotective strategies to increase transplantation success. The aim is to translate this research to the clinic and find a cure for blindness.
- Website
- https://research.bond.edu.au/en/organisations/clem-jones-centre-for-regenerative-medicine
- Organisation type
- University research centre
- Number of research staff
- Up to 20 research staff
- Address
- Faculty of Health Sciences & Medicine (building 5), Bond University, 14 University Drive, Robina QLD 4229
Strengths and capabilities
- Stem cell science and differentiation
- Stem cell transplantation
- Tissue reconstruction
- Tissue engineering
- Regenerative medicine
- Retinal neuroscience
- Vision science, age-related macular degeneration
- Retinal degeneration
- Biomaterials, nanoparticles, biomembranes
- Retinal cell biology, pigment epithelial cells, photoreceptors
- Drug development
- Anti-inflammatory and antioxidant drugs
- Retinal disease models
- Retinal surgery.
Facilities and major equipment
- Physical Containment Class 1 Laboratory (PC1)
- Animal holding room
- Tissue culture facilities
- Molecular biology laboratory
- Flow cytometry facility
- Scanning electron microscopy
- Confocal microscopy
- Advanced ophthalmology facility (Micron imaging system with image guided optical coherence tomography (OCT), electroretinography (ERG) and multi-focal ERG)
- Live cell microscopy
- Small animal surgery facilities
- Cryostat and histological equipment
- Nano-fibre membrane electrospinning facility.
Lead researchers
- Associate Professor Nigel Barnett— Retinal degeneration mechanisms and the development of innovative therapies forertinal disease conditions such as macular degeneration and glaucoma
- Dr Jason Limnios— Stem cell research and therapies for retinal degenerative diseases using stem cell derived retinal cells
- Adjunct Professor Helen O'Neill— Stem cell biology and immunology, experimental hematology, spleen hematopoiesisis and stromal cell niches.
Achievements of the centre
- Rapid and efficient differentiation of stem cells into retinal cells
- Cell-on-membrane construct for retinal transplantation
- Novel neuroprotective drugs to increase cell survival following transplantation
- IP with several patents in Australia and overseas covering 1) the production of a biocompatible membrane, 2) the differentiation of stem cells into retinal cells.
Key science sectors
More information about the sectors this centre is involved in:
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