Cancer and Ageing Research Program (CARP)

Centre for Genomic and Personalised Health, Translational Research Institue, Queenlsand University of Technology

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rack of plastic test tubes

Half of all global deaths will be from cancer by 2030. The Cancer and Ageing Research Program team of leading and emerging researchers are working to uncover the universal processes of what goes wrong in our cells as we age that allow cancers and ageing diseases to develop. CARP is identifying the changes that do occur in our cells and its genome which makes us age and develop ageing diseases such as cancer, arthritis and Alzheimer's disease. The CARP Team aim to develop therapeutics and treatments that can stop cancers and ageing diseases before they start.

Website
https://www.carp.org.au
Organisation type
  • University Research Centre
Number of research staff
20-100 research staff
Address
37 Kent Street, Woolloongabba QLD 4102

Strengths and capabilities

  • Drug discovery
  • Pre-clinical animal models
  • Ageing and Dementia
  • Combinatorial chemistry
  • High co-throughput screening
  • Molecular and cellular biology
  • Genomics
  • Oncology

Facilities and major equipment

  • InCell Analyzer 2200 and InCell 6500HS
  • Cytell Cell Imaging System
  • DeltaVision Elite and DeltaVision OMX Super Resolution Microscope
  • High Content Holomonitor M4 - Holographic Microscope
  • GE Biacore T200 Surface Plasmon Resonance System
  • Isothermal Titration Calorimetry (ITC)
  • Circular Dichroism Spectrophotometer CD-spec J-1500
  • Physical Containment Class 2 (PC2) laboratory
  • Pre-clinical models laboratory

Lead researchers

  • Prof Derek Richard—Discovered the human SSB family of proteins and their critical role in maintaining genetic stability - Expert on DNA stability and repair.
  • Prof Kenneth O'Byrne—Involved in over 200 clinical trials and with expertise in biomarker identification in biopsies and drug resistance linked to cancer stemness
  • Dr Laura Croft - Rare genetic diseases
  • Dr Amila Suraweera - Role of chromatin remodelling in DNA repair
  • Dr Mark Adams - Targeting cancer cell signalling

Achievements of the centre

  • Established one of Australia's largest multimodal Drug Discovery and development centres.
  • Spun out REPLUCA Pharmaceuticals
  • Spun out Carpe Vitae Pharmaceuticals

Key science sectors

More information about the sectors this centre is involved in:

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