Compounds Australia

Griffith University

Formerly known as Queensland Compound Library, Griffith Institute for Drug Discovery (GRIDD)

Compounds Australia provides services critical to the Australian drug discovery research sector. Based around a custom-designed suite of advanced robotics and software, Compounds Australia facilitates collaborative drug discovery nationally and internationally:

• Specialist Open Access Compound Libraries: Researchers can access our carefully curated libraries, tailored to specific research needs.
• Compound Processing: Our sophisticated robotics and advanced processing capabilities enable miniaturisation and acceleration of hit identification screens, allowing researchers to screen more compounds with higher accuracy and efficiency.
• Compound Storage: We provide industry-standard automated storage for member compounds, ensuring the integrity and longevity of screening libraries.
• Compound Management: By outsourcing compound management to Compounds Australia, researchers can focus more on their research and less on logistical concerns.

Website

https://www.griffith.edu.au/griffith-sciences/compounds-australia

Organisation type

• University Research Centre
• National Collaborative Research Infrastructure Scheme facility
• Research Infrastructure Co-investment Fund facility
• Australian Research Council Linkage Infrastructure, Equipment and Facilities (LIEF)
• Not-for-profit
• Other (Australian Cancer Research Foundation Centre for Sample Management and Logistics)

Number of research staff

Up to 20 research staff

Address

Building N75, Institute for Biomedicine and Glycomics, Griffith University, Brisbane Innovation Park, 46 Don Young Rd, Nathan QLD 4111

Strengths and capabilities

• Accelerate drug discovery by enabling low-, med-, and high- throughput compound screening
• Industry standard compound storage and sample processing
• Management and provision of open-and closed-access compound libraries
• Smart Compounds – Online search portal for available open-access samples
• Sample quality control via LC-MS
• Provide compounds in assay ready microplates (flexible formats)
• Nanolitre and microlitre liquid handling
• Microtube- and microplate storage and handling

Facilities and major equipment

• Automated storage for a capacity of 1.5 million microtubes
• Automated storage for a capacity to hold 15,000 microplates
• Automated sample processing platforms with microliter and nanoliter liquid handling capability
• Centralised robotics to automate microplate movement and sample processing
• Full data handling of Inventory/Sample throughout storage and processing for sample tracking and auditing
• Automated plate sealing, seal removal and centrifugation and labelling
• Automated microtube capping, de-capping and 2D-barcode scanning
• Beckman Echo 650/550 acoustic liquid handlers for accurate nanolitre dispensing from acoustic compatible storage plates and tubes in customisable formats
• Multiple liquid handlers for microlitre liquid handling (microtube processing, microplate replications/reformatting and a full suite of sample cherrypicking and serial dilution capabilities)

Achievements of the centre

• Compounds Australia stores the 330,000 Australian Drug Discovery Library (ADDL) of the Australian Lead Identification Consortium. Learn more
• Recent infrastructure and library upgrades, the TIA facility and ACRF Centre for Compound Management and Logistics is looking to support more researchers and accelerate more drug discovery projects than ever. Learn more

Key science sectors

More information about the sectors this centre is involved in:

• Biotechnology
• Health and medical