The Centre for Genomics and Personalised Health translates knowledge from genomics research to improve human health, by discovering better methods of diagnosing disease, developing targeted treatments based on genetics. The Centre spans the design, development, and application of methods for genomic discovery, analysis and translation to advance genomics-driven healthcare and drive outcomes in the real world of clinical and personalised health.

Website

https://research.qut.edu.au/cgph/

Organisation type

• University research centre
• National collaborative research infrastructure scheme

Number of research staff

20-100 research staff

Address

60 Musk Avenue, Kelvin Grove QLD 4059

Strengths and capabilities

• NATA accredited diagnostic testing
• Next generation Sequencing (NGS)
• Case-control population resources
• Norfolk Island isolated population
• Population database of molecular and epidemiological data
• Whole genome and gene expression analyses
• Epigenetic analyses
• Bioinformatics
• Cell culture
• Somatic mutations
• Spatial tissue profiling

Facilities and major equipment

• NATA accredited Molecular Diagnostic facility (PC2)
• Molecular biology research laboratory (PC2)
• Member of the TIA Qld node consortium
• Ion Torrent, Illumina and Nanopore sequencers
• MassArray system
• qPCR systems
• Ancient DNA clean facility (PC2)
• Cell culture
• Nanostring spatial tissue profiler

Lead researchers

• Distinguished Professor Lyn Griffiths is a molecular geneticist with more than 30 years’ research experience. Her work focuses on identifying genes involved in common traits and disorders including migraine, cardiovascular disease, memory, dementia and concussion.
• Professor Derek Richard’s research seeks to understand how DNA repair systems function to protect our genetic code from disease causing mutations and how these protective processes go wrong with age, driving disease initiation.
• Professor Nathan Subramaniam’s research focuses on the study of liver injury and understanding how the liver regulates iron homeostasis.
• Professor Dale Nyholt is a Human Geneticist expert in the statistical analysis of common complex traits. Hisexpertise spans statistical genetic and genomic analysis, epidemiology, bioinformatics and biostatistics.

Achievements of the centre

• Building on our establishment of the first NATA accredited Next generation Sequencing diagnostic service in Australia in 2013, in 2023 we developed an improved diagnostic panel for the detection of stroke syndromes, hemiplegic migraine, epilepsy and ataxia, significantly increasing diagnostic detection rates.
• CGPH links Queensland patients with clinical trials to evaluate treatments to improve outcomes for people with cancer, thanks to a new collaboration with non-profit research organisation Omico and the PrOSPeCT program.
• Facilitates Bridge and BridgeTech commercialisation Training Programs in collaboration with consortium of pharmaceutical companies, universities and affiliates.
• Collaborative partnership with Australian Department of Defence to use new DNA technology to identify fallen solider remains.

Key science sectors

More information about the sectors this centre is involved in:

• Biotechnology
• Health and medical